Life Sciences

Research and development of the technology of medical stents manufacturing by means of laser milling

We established that at laser stent manufacturing by means of direct laser milling technology there is a possibility to create “pockets” in the stent’s walls with given depth, shape and size. These pockets are used for drug deposition and could not be formed using ordinary laser cutting techniques. Moreover, it is also possible to wary the stent’s filament thickness (up to 20 mkm) thus increasing the flexibility and elasticity when filament’s width increases (from 0.5 to 1 mm).

The Multipurpose hardware and software system of non-invasive diagnostic with synergetic approach to therapies and with diagnostic and therapeutic sign validation

Based on the analysis of existing tools and methods oftherapy justified technical performance requirements of amultifunctional complex therapy. Methods for the formation ofelectromagnetic fields, which take into account the low-frequency resonant nature of physico- shemical and biological processes in the body systems, individual organs, cells and molecules. Presents views on the furtherdevelopment of physical therapy at the molecular andcellular level. The principles of construction of the basicunits of multi-channel and multi-stage inductor generator forextended range 1 Hz ...

The development of new probiotics based on lactic acid bacteria genus Lactobacillus

Multiprobiotic drug was created on a base of 5 strains of bacteria p. Lactobacillus. The product is characterized by high antagonistic activity in point of pathogenic and conditionally pathogenic bacteria, ability to adhesion of epithelial cells of the intestinal mucosa and resistance to aggressive gastrointestinal mediums. Probiotic is showed antimutagenic and antiherpetic activity, immunological regulations and involved in metabolism of bile and gonadal hormones.

Research and development of DSP-clinical audiometer for diagnostic of diseases of an ear

Proposed new structure of the patented DSP-audiometr, and developed its new Simulink-based model, which is provided and playback keys (in the range from 125 Hz to 16 kHz), broadband and narrowband test stimulus, and the implementation of a number of above-threshold procedures (tests Fowler, Lusher, SISI and Stenger).

Development of an undestracting tomographic means for complex impedance and structural parameters of spatially spased nonmutual objects definition.

Methodological and engineering bases for definition internal structure and condition of nonreciprocal spatially distributed objects or their parts by means of an evaluation of a directional distribution of complex electric impedance are developed. New methods of diagnostic and the concept of construction of systems on their basis are developed.

The trial model of the system for oncological disease treatment with photodynamic therapy method.

The treatment of the oncological diseases with photodynamic therapy method (PDT) is based on the cancerous cells selective destruction owing to the residues of photochemical reactions taken place into the malignant tumors those have accumulated photosensitizer selectively when dosed exposing of the light with specific wavelength.

Research and development of the technology of laser cutting of medical implants (stents).

There was developed a highly efficient technology of medical stents' manufacturing  by means of focused laser beam.

 The developed technology lets us to cut stents  from tube workpieces (material – stainless steel, nitinol etc.) with any complexity of the stent's pattern. In order to implement the developed technology a trial version of industrial laser system that consists of Q-switched YAG laser, beam delivery and focusing system, assyst gas delivery system, monitor and control system and workpiece movement and protection system was developed.

Development of non-invasive technologies and high resolution systems for early diagnosis of cardiovascular diseases

Theoretical foundations of non-invasive high resolution technologies for early diagnosis of cardiovascular system are given. Algorithms and programs for early diagnosis of cardiovascular system based on the development of techniques for pattern recognition of structural components electrocardiogram are developed. The technique of component analysis of heart rate variability based on orthogonal dyadic wavelet analysis is presented.